piperidine, 4-[(3-fluorophenyl)methyl]-

piperidine, 4-[(3-fluorophenyl)methyl]- - Names and Identifiers

Name	4-(3-fluorobenzyl)piperidine
Synonyms	LogP 4-(3-fluorobenzyl)piperidine 4-(3-FLUORO-BENZYL)-PIPERIDINE 4-[(3-fluorophenyl)Methyl]piperidine Piperidine, 4-[(3-fluorophenyl)methyl]- piperidine, 4-[(3-fluorophenyl)methyl]-
CAS	202126-85-0
InChI	InChI=1/C12H16FN/c13-12-3-1-2-11(9-12)8-10-4-6-14-7-5-10/h1-3,9-10,14H,4-8H2

piperidine, 4-[(3-fluorophenyl)methyl]- - Physico-chemical Properties

Molecular Formula	C12H16FN
Molar Mass	193.26
Density	1.045g/cm³
Boling Point	278.583°C at 760 mmHg
Flash Point	122.283°C
Vapor Presure	0.004mmHg at 25°C
Storage Condition	2-8°C
Refractive Index	1.513

piperidine, 4-[(3-fluorophenyl)methyl]- - Introduction

4-(3-fluorobenzyl)piperidine is a compound with the chemical formula C11H12FNO, which contains a piperidine ring and a benzyl group, and a fluorine atom in the benzyl group.

In terms of properties, 4-(3-fluorobenzyl)piperidine is a solid, colorless or slightly yellow crystal, soluble in organic solvents such as ethanol and dichloromethane. It is a strong basic compound, due to the basic piperidine ring, can react with acid to form a salt.

In Terms of Use, 4-(3-fluorobenzyl)piperidine is often used as an intermediate in organic synthesis. It can be used to synthesize other organic compounds, such as drugs, dyes and pesticides. In addition, it can also be used as a ligand in organic catalytic reactions.

In terms of preparation method, 4-(3-fluorobenzyl)piperidine can be obtained by benzyl chloride reaction and benzylamine and fluoroacetic acid reaction. First, benzylamine reacts with fluoroacetic acid to generate N-(3-fluorobenzyl) benzylamine, and then fluorine atoms are introduced into the benzyl group through chlorination reaction to obtain the target product 4-(3-fluorobenzyl)piperidine.

In terms of safety information, 4-(3-fluorobenzyl)piperidine has no special safety hazards under normal use conditions. However, it is an irritating compound, and contact with the skin, eyes, etc. may cause irritation and redness. Appropriate protective measures should be taken during use, such as wearing gloves and goggles. In addition, it should also be stored in a cool, dry place, away from fire and oxidants. In case of any accident, seek medical help immediately.

Last Update：2024-04-10 22:31:16